Who will score the first touchdown in Week 6: 49ers vs Buccaneers?
McCaffrey Leads Betting as First TD Scorer in 49ers-Bucs Clash
The undefeated San Francisco 49ers (5–0) take on the struggling Tampa Bay Buccaneers (1–4) in Week 6 of the 2025 NFL season. As fans and bettors look toward first touchdown scorer predictions, all eyes are on San Francisco's offensive stars. Christian McCaffrey leads the league in TDs and has scored in every game this season. Deebo Samuel and Brandon Aiyuk remain explosive options in the red zone. For the Buccaneers, Mike Evans and Rachaad White are their top scoring threats. With San Francisco heavily favored by over 10 points and the total line around 44, the most likely scenario is a 49ers touchdown to start. The poll expires before kickoff on October 12, giving fans a chance to weigh in early.
Options
- Christian McCaffrey
- Deebo Samuel
- Brandon Aiyuk
- Mike Evans
- Rachaad White